Please keep in mind that blood will get mixed in with mucous and drainage, and may appear to be a lot. Aggressive bleeding consists of a sustained oozing/streaming flow of blood from the nostrils. Only if you experience this type of aggressive bleeding for more than 30-40 minutes, spray 2 to 3 puffs of Afrin Nasal Spray into each nostril, followed by two additional puffs every 10 minutes until bleeding stops. Afrin may be purchased over-the-counter. If a large volume of bleeding continues, please call our office.